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Prolactin secretion is controlled by prolactin inhibitor factor that is secreted from hypothalamus, other factors like vaso active inhibitory peptide (VIP) and Thyroid relising hormone (TRH) cause to increase prolactin secretion (1). In fact, TRH in addition to increasing TSH causes to rise prolactin level (2).
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Serum TSH levels were found to be positively correlated with prolactin levels in the cases (r=0.4, p=0.01).
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We could find no correlation between serum TSH and PRL levels, suggesting that the purported association between a decreased thyroid state and breast cancer ...
Jan 29, 2019 · Study results also revealed a positive correlation between low thyroid-stimulating hormone (TSH) levels and elevated serum prolactin levels (P ...
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Sep 17, 2024 · Prolactin has a positive correlation with TSH in both hyperthyroidism and hypothyroidism. Both prolactin and thyroid hormone levels should be estimated in ...
Therefore, reduced thyroid hormone levels will lead to more PRL synthesis (12). In fact, in hypothyroidism, PRL clearance from circulation is also reduced (13).
Primary hypothyroidism can cause both hyperprolactinemia and pituitary hyperplasia. The degree of hyperprolactinemia is generally modest.