WO2008146691A1 - 肝炎の予防又は治療のための医薬組成物 - Google Patents

肝炎の予防又は治療のための医薬組成物 Download PDF

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Publication number
WO2008146691A1
WO2008146691A1 PCT/JP2008/059414 JP2008059414W WO2008146691A1 WO 2008146691 A1 WO2008146691 A1 WO 2008146691A1 JP 2008059414 W JP2008059414 W JP 2008059414W WO 2008146691 A1 WO2008146691 A1 WO 2008146691A1
Authority
WO
WIPO (PCT)
Prior art keywords
hepatitis
prevention
treatment
pharmaceutical composition
alkyl group
Prior art date
Application number
PCT/JP2008/059414
Other languages
English (en)
French (fr)
Japanese (ja)
Inventor
Takaichi Shimozato
Takashi Kagari
Hiromi Doi
Original Assignee
Daiichi Sankyo Company, Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Sankyo Company, Limited filed Critical Daiichi Sankyo Company, Limited
Priority to EP08764487A priority Critical patent/EP2149549A4/en
Priority to JP2009516274A priority patent/JPWO2008146691A1/ja
Publication of WO2008146691A1 publication Critical patent/WO2008146691A1/ja
Priority to US12/624,214 priority patent/US20100081702A1/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/335Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/38Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/22Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
PCT/JP2008/059414 2007-05-25 2008-05-22 肝炎の予防又は治療のための医薬組成物 WO2008146691A1 (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP08764487A EP2149549A4 (en) 2007-05-25 2008-05-22 PHARMACEUTICAL COMPOSITION FOR THE PREVENTION OR TREATMENT OF HEPATITIS
JP2009516274A JPWO2008146691A1 (ja) 2007-05-25 2008-05-22 肝炎の予防又は治療のための医薬組成物
US12/624,214 US20100081702A1 (en) 2007-05-25 2009-11-23 Pharmaceutical composition for prophylaxis or treatment of hepatitis

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007-138771 2007-05-25
JP2007138771 2007-05-25

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US12/624,214 Continuation US20100081702A1 (en) 2007-05-25 2009-11-23 Pharmaceutical composition for prophylaxis or treatment of hepatitis

Publications (1)

Publication Number Publication Date
WO2008146691A1 true WO2008146691A1 (ja) 2008-12-04

Family

ID=40316830

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/059414 WO2008146691A1 (ja) 2007-05-25 2008-05-22 肝炎の予防又は治療のための医薬組成物

Country Status (5)

Country Link
US (1) US20100081702A1 (esCached)
EP (1) EP2149549A4 (esCached)
JP (1) JPWO2008146691A1 (esCached)
TW (1) TW200906389A (esCached)
WO (1) WO2008146691A1 (esCached)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015505536A (ja) * 2012-01-20 2015-02-23 アクセラ インク. 疾患の処置のための置換された複素環化合物

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002006228A1 (fr) 2000-07-19 2002-01-24 Ube Industries, Ltd. Procede de production de 5-fluorooxyindole et procede de production d'un produit intermediaire de celui-ci
WO2003059880A1 (fr) 2002-01-11 2003-07-24 Sankyo Company, Limited Derive d'amino-alcool ou derive d'acide phosphonique et composition medicamenteuse les contenant
JP2003267974A (ja) * 2002-01-11 2003-09-25 Sankyo Co Ltd アミノアルコ−ル誘導体を含有する医薬組成物
WO2005079788A1 (ja) 2004-02-24 2005-09-01 Sankyo Company, Limited アミノアルコール化合物
WO2006137509A1 (ja) * 2005-06-24 2006-12-28 Daiichi Sankyo Company, Limited Ppar調節剤を含有する医薬組成物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100812578B1 (ko) * 2000-07-13 2008-03-13 상꾜 가부시키가이샤 아미노알코올 유도체
WO2005005383A1 (ja) * 2003-07-11 2005-01-20 Sankyo Company, Limited アミノアルコール化合物
JP2006188452A (ja) * 2005-01-06 2006-07-20 Sankyo Co Ltd アミノアルコール化合物を含有する医薬組成物

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002006228A1 (fr) 2000-07-19 2002-01-24 Ube Industries, Ltd. Procede de production de 5-fluorooxyindole et procede de production d'un produit intermediaire de celui-ci
WO2003059880A1 (fr) 2002-01-11 2003-07-24 Sankyo Company, Limited Derive d'amino-alcool ou derive d'acide phosphonique et composition medicamenteuse les contenant
JP2003267974A (ja) * 2002-01-11 2003-09-25 Sankyo Co Ltd アミノアルコ−ル誘導体を含有する医薬組成物
WO2005079788A1 (ja) 2004-02-24 2005-09-01 Sankyo Company, Limited アミノアルコール化合物
WO2006137509A1 (ja) * 2005-06-24 2006-12-28 Daiichi Sankyo Company, Limited Ppar調節剤を含有する医薬組成物

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
INOUE K.: "C-gata Kan'en Virus to Cyclosporin A", IGAKU NO AYUMI, vol. 193, no. 12, 2000, pages 951 - 954, XP003004368 *
See also references of EP2149549A4 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015505536A (ja) * 2012-01-20 2015-02-23 アクセラ インク. 疾患の処置のための置換された複素環化合物

Also Published As

Publication number Publication date
TW200906389A (en) 2009-02-16
US20100081702A1 (en) 2010-04-01
EP2149549A1 (en) 2010-02-03
JPWO2008146691A1 (ja) 2010-08-19
EP2149549A4 (en) 2012-01-04

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