WO1992014438A2 - Prostacycline and carbacycline derivatives as agents for treating feverish complaints - Google Patents
Prostacycline and carbacycline derivatives as agents for treating feverish complaints Download PDFInfo
- Publication number
- WO1992014438A2 WO1992014438A2 PCT/DE1992/000100 DE9200100W WO9214438A2 WO 1992014438 A2 WO1992014438 A2 WO 1992014438A2 DE 9200100 W DE9200100 W DE 9200100W WO 9214438 A2 WO9214438 A2 WO 9214438A2
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- diseases
- treatment
- agent
- prostacyclin
- carbacyclin derivatives
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Abstract
Description
Claims
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP4504121A JPH06507381A (en) | 1991-02-12 | 1992-02-11 | Prostacyclin and carbacyclin derivatives as medicines for the treatment of febrile diseases |
AU12433/92A AU660449B2 (en) | 1991-02-12 | 1992-02-11 | Prostacycline and carbacycline derivatives as agents for treating feverish complaints |
KR1019930702386A KR930702990A (en) | 1991-02-12 | 1993-08-11 | Prostacyclin- and carbacycline derivatives for the treatment of fibrotic diseases |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4104607A DE4104607A1 (en) | 1991-02-12 | 1991-02-12 | PROSTACYCLIN AND CARBACYCLINE DERIVATIVES AS A MEDIUM FOR TREATING FEVERED DISEASES |
DEP4104607.2 | 1991-02-12 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO1992014438A2 true WO1992014438A2 (en) | 1992-09-03 |
WO1992014438A3 WO1992014438A3 (en) | 1993-01-07 |
Family
ID=6425075
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/DE1992/000100 WO1992014438A2 (en) | 1991-02-12 | 1992-02-11 | Prostacycline and carbacycline derivatives as agents for treating feverish complaints |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP0571462A1 (en) |
JP (1) | JPH06507381A (en) |
KR (1) | KR930702990A (en) |
AU (1) | AU660449B2 (en) |
CA (1) | CA2104024A1 (en) |
DE (1) | DE4104607A1 (en) |
WO (1) | WO1992014438A2 (en) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0623346A4 (en) * | 1991-04-11 | 1994-08-29 | Toray Industries | Inhibitor for metastasis of malignant tumor. |
US5496850A (en) * | 1991-04-11 | 1996-03-05 | Toray Industries, Inc. | Antimetastasis agent of malignant tumors |
EP0925787A1 (en) * | 1997-02-27 | 1999-06-30 | Toray Industries, Inc. | Drugs for ameliorating pulmonary circulation |
EP0947195A1 (en) * | 1997-03-14 | 1999-10-06 | Toray Industries, Inc. | Protective agents for cells constituting nervous system |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4124695C2 (en) * | 1991-07-22 | 1994-12-22 | Blitstein Willinger Eveline Dr | Use of carbacyclin derivatives for the treatment of psoriasis vulgaris |
DE4124693A1 (en) * | 1991-07-22 | 1993-01-28 | Schering Ag | Use of carbocycline derivs. - esp. iloprost, cicaprost, eptaloprost, beraprost or ciprostene, for treatment of vitiligo |
DE4226615C1 (en) * | 1992-08-07 | 1994-05-19 | Schering Ag | Use of prostane derivatives for the treatment of chronic polyarthritis |
DE19530884C2 (en) * | 1995-08-11 | 1997-07-31 | Schering Ag | Use of prostane derivatives and their combination with antibiotics for the treatment of bacterial meningitis |
JPH11228417A (en) * | 1998-02-06 | 1999-08-24 | Teijin Ltd | Neuropathy remedy |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0011591A1 (en) * | 1978-10-19 | 1980-05-28 | Schering Aktiengesellschaft | Prostane derivatives, their production and pharmaceutical compositions containing them |
EP0084856A1 (en) * | 1982-01-20 | 1983-08-03 | Toray Industries, Inc. | 5,6,7-Trinor-4, 8-inter-m-phenylene prostaglandin I2 derivatives |
EP0099538A1 (en) * | 1982-07-13 | 1984-02-01 | Schering Aktiengesellschaft | Carbacyclines, process for their preparation and their use as medicines |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4256883A (en) * | 1979-03-14 | 1981-03-17 | Research Corporation | Pyridoza prostacyclin analogues and N-oxides thereof |
DE3740838A1 (en) * | 1987-11-27 | 1989-06-08 | Schering Ag | CYCLODEXTRINCLATHRATE OF 5-CYANO-PROSTACYCLINE DERIVATIVES AND THEIR USE AS MEDICINAL PRODUCTS |
EP0330025B1 (en) * | 1988-02-23 | 1994-10-12 | Teijin Limited | Antidiabetic composition comprising isocarbacyclin derivative |
-
1991
- 1991-02-12 DE DE4104607A patent/DE4104607A1/en not_active Withdrawn
-
1992
- 1992-02-11 EP EP92904665A patent/EP0571462A1/en not_active Withdrawn
- 1992-02-11 JP JP4504121A patent/JPH06507381A/en active Pending
- 1992-02-11 CA CA002104024A patent/CA2104024A1/en not_active Abandoned
- 1992-02-11 AU AU12433/92A patent/AU660449B2/en not_active Ceased
- 1992-02-11 WO PCT/DE1992/000100 patent/WO1992014438A2/en not_active Application Discontinuation
-
1993
- 1993-08-11 KR KR1019930702386A patent/KR930702990A/en not_active Application Discontinuation
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0011591A1 (en) * | 1978-10-19 | 1980-05-28 | Schering Aktiengesellschaft | Prostane derivatives, their production and pharmaceutical compositions containing them |
EP0084856A1 (en) * | 1982-01-20 | 1983-08-03 | Toray Industries, Inc. | 5,6,7-Trinor-4, 8-inter-m-phenylene prostaglandin I2 derivatives |
EP0099538A1 (en) * | 1982-07-13 | 1984-02-01 | Schering Aktiengesellschaft | Carbacyclines, process for their preparation and their use as medicines |
Non-Patent Citations (6)
Title |
---|
Biochemical Pharmacology, Band 41, Nr. 8, 1991, Pergamon Press plc, (GB), M. KAINOH et al.: "Enhancement by beraprost sodium, a stable analogue of prostacyclin, in thrombomodulin expression on membrane surface of cultured vascular endothelial cells via increase in cyclic AMP level", Seiten 1135-1140, siehe Zusammenfassung; Seite 1137, Zeile 39 - Seite 1140, Zeile 4 * |
Blood, Band 76, Nr. 10, Suppl. 1, 15. November 1990, D.J. CRUTCHLEY et al.: "The stable prostacyclin analog, iloprost, is a potent inhibitor of human monocyte procoagulant activity", Seite 503a, siehe das ganze Dokument * |
Blood, Band 78, Nr. 2, 15. Juli 1991, D.J. CRUTCHLEY et al.: "The stable prostacyclin analog, iloprost, and prostaglandin E, inhibit monocyte procoagulant activity in vitro", Seiten 382-386, siehe das ganze Dokument * |
Chimical Intensive Care, Band 3, Nr. 2 (Suppl.), 1992, A. J\RRES et al.: "Specific downregulation of TNFalpha in endotoxin-stimulated mononuclear leukocytes by the prostacyclin analogue iloprost", Seite 21, siehe das ganze Dokument * |
Chimical Intensive Care, Band 3, Nr. 2 (Suppl.), 1992, U. H[HNLE et al.: "Protective effect of iloprost, a prostacyclin analogue, in experimental endotoxic shock", Seite 8, siehe das ganze Dokument * |
Infection and Immunity, Band 59, Nr. 10, Oktober 1991, American Society for Microbiology, K. SLIWA et al.: "Prevention of murine cerebral malaria by a stable prostacyclin analog", Seiten 3846-3848, siehe das ganze Dokument * |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0623346A4 (en) * | 1991-04-11 | 1994-08-29 | Toray Industries | Inhibitor for metastasis of malignant tumor. |
EP0623346A1 (en) * | 1991-04-11 | 1994-11-09 | Toray Industries, Inc. | Inhibitor for metastasis of malignant tumor |
US5496850A (en) * | 1991-04-11 | 1996-03-05 | Toray Industries, Inc. | Antimetastasis agent of malignant tumors |
EP0925787A1 (en) * | 1997-02-27 | 1999-06-30 | Toray Industries, Inc. | Drugs for ameliorating pulmonary circulation |
EP0947195A1 (en) * | 1997-03-14 | 1999-10-06 | Toray Industries, Inc. | Protective agents for cells constituting nervous system |
EP0947195A4 (en) * | 1997-03-14 | 1999-12-01 | Toray Industries | Protective agents for cells constituting nervous system |
Also Published As
Publication number | Publication date |
---|---|
AU1243392A (en) | 1992-09-15 |
EP0571462A1 (en) | 1993-12-01 |
JPH06507381A (en) | 1994-08-25 |
WO1992014438A3 (en) | 1993-01-07 |
DE4104607A1 (en) | 1992-08-13 |
AU660449B2 (en) | 1995-06-29 |
CA2104024A1 (en) | 1992-08-13 |
KR930702990A (en) | 1993-11-29 |
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