Extreme close up on the character Dren from the movie 'Splice'
Photo via Les Films Séville

What is Dren from ‘Splice’ and how were they created?

Are you sure you want to know?

In 2010, the sci-fi horror movie Splice hit theaters to a wide range of opinions, splitting critics and audiences almost directly down the middle. 

Recommended Videos

Starring Adrien Brody and Sarah Polley as genetic engineers Clive and Elsa, the movie is a good example of the saying, “be careful what you wish for.” Clive and Elsa thought they knew what they were doing when they started splicing different DNA together to create a new hybrid species. But as we all know, playing God never goes as planned. The resulting creature is dangerous and deadly and causes irrefutable havoc for the pair. 

Mixing in psychosexual elements that leave the viewer feeling both perturbed and disturbed, Splice unsurprisingly was met with mixed reviews and as a result, fell short of earning back the $30 million the studio put into the film. However, thanks in part to Guillermo del Toro’s executive producing credits on the film and his presence in the movie industry to this day, including his recent anthology series Cabinet of Curiosities, the movie has seen a resurgence on streaming. Now more than ever, horror and sci-fi lovers have set their sights on Splice, and because the movie can be a little tough to wrap your head around, we’ve gone ahead and done it for you.

What exactly is Dren and how and how were they created?

The movie starts out with Clive and Elsa — two genetic engineers at a medical company called Newstead — helping deliver the birth of a worm-like creature named Fred, who they created by splicing together different animal DNA. They place Fred in a tank with another worm-like creature named Ginger. Fred and Ginger end up mating, and Clive and Elsa use their embryo to splice together with human DNA to create Hitch-50, aka Dren.

At first, Clive and Elsa had no intention of keeping Dren, but after Elsa experiences an emotional connection to the hybrid creature they decide to keep Dren alive. What results is a rollercoaster ride of twists and turns, a few fatalities, and more than enough uncomfortable scenes to give you the heebie-jeebies.

If you’re curious as to why we refer to Dren as they and not she, well, you’ll just have to watch the movie. Here’s more information on how you can stream the film.


We Got This Covered is supported by our audience. When you purchase through links on our site, we may earn a small affiliate commission. Learn more
related content
Read Article Giancarlo Esposito officially joins MCU, but the crucial point of his deal has already disappeared into oblivion
Giancarlo Esposito joins MCU
Read Article Latest Marvel News: Ben Affleck threatens to invade the MCU as Kevin Feige calls out his big problem with ‘Deadpool 3’ — and he’s got a point
Deadpool forms a frame with his hands with Charlie Cox's Daredevil and Ben Affleck's Daredevil behind him
Read Article Hugh Jackman’s legendary new role might just make Taron Egerton more likely to become the next Wolverine
Taron Egerton and Hugh Jackman arrive for the European premiere of 'Eddie The Eagle' at Odeon Leicester Square on March 17, 2016 in London, England.
Read Article ‘The Idea Of You’: Is August Moon A Real Band?
Nicholas Galitzine as 'Hayes Campbell', Raymond Cham Jr. as 'Oliver', Jaiden Anthony as 'Adrian', Viktor White as 'Simon' and Dakota Adan as 'Rory' star in THE IDEA OF YOU
Read Article Marvel confirms controversial ‘Captain America 4’ leak, and now everyone’s saying the same thing
Anthony Mackie's Sam Wilson wields the Captain America shield superimposed over an orange-hued poster for Avengers: Endgame
Related Content
Read Article Giancarlo Esposito officially joins MCU, but the crucial point of his deal has already disappeared into oblivion
Giancarlo Esposito joins MCU
Read Article Latest Marvel News: Ben Affleck threatens to invade the MCU as Kevin Feige calls out his big problem with ‘Deadpool 3’ — and he’s got a point
Deadpool forms a frame with his hands with Charlie Cox's Daredevil and Ben Affleck's Daredevil behind him
Read Article Hugh Jackman’s legendary new role might just make Taron Egerton more likely to become the next Wolverine
Taron Egerton and Hugh Jackman arrive for the European premiere of 'Eddie The Eagle' at Odeon Leicester Square on March 17, 2016 in London, England.
Read Article ‘The Idea Of You’: Is August Moon A Real Band?
Nicholas Galitzine as 'Hayes Campbell', Raymond Cham Jr. as 'Oliver', Jaiden Anthony as 'Adrian', Viktor White as 'Simon' and Dakota Adan as 'Rory' star in THE IDEA OF YOU
Read Article Marvel confirms controversial ‘Captain America 4’ leak, and now everyone’s saying the same thing
Anthony Mackie's Sam Wilson wields the Captain America shield superimposed over an orange-hued poster for Avengers: Endgame
Author
Cody Raschella
Cody Raschella is a Staff Writer and occasional Editor who has been with WGTC since 2021. He is a closeted Swiftie (shh), a proud ‘Drag Race’ fan (yas), and a hopeless optimist (he still has faith in the MCU). His passion for writing has carried him across various mediums including journalism, copywriting, and creative writing, the latter of which has been recognized by Writer’s Digest. He received his bachelor's degree from California State University, Northridge.