WO2009158571A8 - Heteroaryl compounds and uses thereof - Google Patents
Heteroaryl compounds and uses thereof Download PDFInfo
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- WO2009158571A8 WO2009158571A8 PCT/US2009/048784 US2009048784W WO2009158571A8 WO 2009158571 A8 WO2009158571 A8 WO 2009158571A8 US 2009048784 W US2009048784 W US 2009048784W WO 2009158571 A8 WO2009158571 A8 WO 2009158571A8
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- heteroaryl compounds
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- pharmaceutically acceptable
- same
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- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms
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- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
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- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/538—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with carbocyclic ring systems
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- C07D471/04—Ortho-condensed systems
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- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
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- C07D487/18—Bridged systems
Abstract
Priority Applications (21)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
BRPI0914682A BRPI0914682B8 (en) | 2008-06-27 | 2009-06-26 | heteroaryl compounds and compositions comprising said compounds |
DK09771102.2T DK2361248T3 (en) | 2008-06-27 | 2009-06-26 | Heteroberl compounds and uses thereof |
NZ589843A NZ589843A (en) | 2008-06-27 | 2009-06-26 | Pyrimidine heteroaryl compounds and uses thereof as protein kinase inhibitors |
EP18195292.0A EP3549934A1 (en) | 2008-06-27 | 2009-06-26 | Heteroaryl compounds and uses thereof |
CN2009801244104A CN102083800A (en) | 2008-06-27 | 2009-06-26 | Heteroaryl compounds and uses thereof |
RU2010151355/04A RU2536584C2 (en) | 2008-06-27 | 2009-06-26 | Heteroaryl compounds and using them |
CA2727455A CA2727455C (en) | 2008-06-27 | 2009-06-26 | Heteroaryl compounds and uses thereof |
JP2011516699A JP2011526299A (en) | 2008-06-27 | 2009-06-26 | Heteroaryl compounds and their use |
EP09771102.2A EP2361248B1 (en) | 2008-06-27 | 2009-06-26 | Heteroaryl compounds and uses thereof |
ES09771102T ES2711249T3 (en) | 2008-06-27 | 2009-06-26 | Heteroaryl compounds and uses thereof |
KR1020187011709A KR101955914B1 (en) | 2008-06-27 | 2009-06-26 | Heteroaryl compounds and uses thereof |
MX2010014029A MX2010014029A (en) | 2008-06-27 | 2009-06-26 | Heteroaryl compounds and uses thereof. |
MX2015012477A MX360970B (en) | 2008-06-27 | 2009-06-26 | Heteroaryl compounds and uses thereof. |
MX2013013212A MX357627B (en) | 2008-06-27 | 2009-06-26 | Heteroaryl compounds and uses thereof. |
AU2009262068A AU2009262068C1 (en) | 2008-06-27 | 2009-06-26 | Heteroaryl compounds and uses thereof |
KR1020167034131A KR101892989B1 (en) | 2008-06-27 | 2009-06-26 | Heteroaryl compounds and uses thereof |
IL209969A IL209969A (en) | 2008-06-27 | 2010-12-13 | Heteroaryl compounds and uses thereof |
ZA2010/09216A ZA201009216B (en) | 2008-06-27 | 2010-12-22 | Heteroaryl compounds and uses thereof |
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US11590167B2 (en) | 2016-12-03 | 2023-02-28 | Juno Therapeutic, Inc. | Methods and compositions for use of therapeutic T cells in combination with kinase inhibitors |
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