WO2009124176A8 - Substituted 1,3-cyclopentadione attenuated endothelial inflammation and endothelial-monocyte interactions - Google Patents
Substituted 1,3-cyclopentadione attenuated endothelial inflammation and endothelial-monocyte interactions Download PDFInfo
- Publication number
- WO2009124176A8 WO2009124176A8 PCT/US2009/039272 US2009039272W WO2009124176A8 WO 2009124176 A8 WO2009124176 A8 WO 2009124176A8 US 2009039272 W US2009039272 W US 2009039272W WO 2009124176 A8 WO2009124176 A8 WO 2009124176A8
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- endothelial
- cyclopentadione
- substituted
- attenuated
- inflammation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
- C07C49/707—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups a keto group being part of a three- to five-membered ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/10—Systems containing only non-condensed rings with a five-membered ring the ring being unsaturated
Abstract
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA2720546A CA2720546A1 (en) | 2008-04-02 | 2009-04-02 | Substituted 1,3-cyclopentadione attenuated endothelial inflammation and endothelial-monocyte interactions |
JP2011503164A JP2011516492A (en) | 2008-04-02 | 2009-04-02 | Attenuation of endothelial inflammation and endothelium-monocyte interaction by substituted 1,3-cyclopentadione |
EP09728126A EP2268600A4 (en) | 2008-04-02 | 2009-04-02 | Substituted 1,3-cyclopentadione attenuated endothelial inflammation and endothelial-monocyte interactions |
AU2009231723A AU2009231723B2 (en) | 2008-04-02 | 2009-04-02 | Substituted 1,3-cyclopentadione attenuated endothelial inflammation and endothelial-monocyte interactions |
CN2009801191272A CN102066303A (en) | 2008-04-02 | 2009-04-02 | Substituted 1,3-cyclopentadione attenuated endothelial inflammation and endothelial-monocyte interactions |
NZ588927A NZ588927A (en) | 2008-04-02 | 2009-04-02 | Substituted 1,3-cyclopentadione attenuated endothelial inflammation and endothelial-monocyte interactions |
MX2010010791A MX2010010791A (en) | 2008-04-02 | 2009-04-02 | Substituted 1,3-cyclopentadione attenuated endothelial inflammation and endothelial-monocyte interactions. |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US4163108P | 2008-04-02 | 2008-04-02 | |
US61/041,631 | 2008-04-02 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2009124176A1 WO2009124176A1 (en) | 2009-10-08 |
WO2009124176A8 true WO2009124176A8 (en) | 2010-11-18 |
Family
ID=41135936
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2009/039272 WO2009124176A1 (en) | 2008-04-02 | 2009-04-02 | Substituted 1,3-cyclopentadione attenuated endothelial inflammation and endothelial-monocyte interactions |
Country Status (10)
Country | Link |
---|---|
US (1) | US20100222262A1 (en) |
EP (1) | EP2268600A4 (en) |
JP (1) | JP2011516492A (en) |
KR (1) | KR20110010603A (en) |
CN (1) | CN102066303A (en) |
AU (1) | AU2009231723B2 (en) |
CA (1) | CA2720546A1 (en) |
MX (1) | MX2010010791A (en) |
NZ (1) | NZ588927A (en) |
WO (1) | WO2009124176A1 (en) |
Families Citing this family (4)
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US8158160B2 (en) | 2001-11-13 | 2012-04-17 | Eric Hauser Kuhrts | Anti-inflammatory cyclooxygenase inhibitors |
US20110275721A1 (en) * | 2008-12-10 | 2011-11-10 | Metaproteomics, Llc | Method for the purification of substituted cyclopent-2-en-1-one congeners and substituted 1,3-cyclopentadione congeners from a complex mixture using countercurrent separation |
AU2013290297B2 (en) * | 2012-07-09 | 2017-11-02 | Kindex Pharmaceuticals, Inc. | Tetrahydro-isohumulone derivatives, methods of making and using |
GB201611738D0 (en) * | 2016-07-05 | 2016-08-17 | Cambridge Entpr Ltd | Biomarkers for inflammatory bowel disease |
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-
2009
- 2009-04-02 JP JP2011503164A patent/JP2011516492A/en active Pending
- 2009-04-02 MX MX2010010791A patent/MX2010010791A/en not_active Application Discontinuation
- 2009-04-02 CA CA2720546A patent/CA2720546A1/en not_active Abandoned
- 2009-04-02 KR KR1020107024543A patent/KR20110010603A/en not_active Application Discontinuation
- 2009-04-02 WO PCT/US2009/039272 patent/WO2009124176A1/en active Application Filing
- 2009-04-02 AU AU2009231723A patent/AU2009231723B2/en not_active Expired - Fee Related
- 2009-04-02 NZ NZ588927A patent/NZ588927A/en not_active IP Right Cessation
- 2009-04-02 EP EP09728126A patent/EP2268600A4/en not_active Withdrawn
- 2009-04-02 CN CN2009801191272A patent/CN102066303A/en active Pending
- 2009-04-02 US US12/417,205 patent/US20100222262A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO2009124176A1 (en) | 2009-10-08 |
NZ588927A (en) | 2013-02-22 |
KR20110010603A (en) | 2011-02-01 |
EP2268600A4 (en) | 2012-03-21 |
AU2009231723A1 (en) | 2009-10-08 |
MX2010010791A (en) | 2011-03-04 |
US20100222262A1 (en) | 2010-09-02 |
CA2720546A1 (en) | 2009-10-08 |
CN102066303A (en) | 2011-05-18 |
EP2268600A1 (en) | 2011-01-05 |
AU2009231723B2 (en) | 2014-04-17 |
JP2011516492A (en) | 2011-05-26 |
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