WO2007067812A3 - Protein kinase modulation by hops and acacia products - Google Patents

Protein kinase modulation by hops and acacia products Download PDF

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Publication number
WO2007067812A3
WO2007067812A3 PCT/US2006/047196 US2006047196W WO2007067812A3 WO 2007067812 A3 WO2007067812 A3 WO 2007067812A3 US 2006047196 W US2006047196 W US 2006047196W WO 2007067812 A3 WO2007067812 A3 WO 2007067812A3
Authority
WO
WIPO (PCT)
Prior art keywords
hops
acacia
products
protein kinase
kinase modulation
Prior art date
Application number
PCT/US2006/047196
Other languages
French (fr)
Other versions
WO2007067812A2 (en
Inventor
Matthew L Tripp
John G Babish
Jeffrey Bland
Amy Jennae Hall
Veera Konda
Linda Pacioretty
Anu Desai
Original Assignee
Metaproteomics Llc
Matthew L Tripp
John G Babish
Jeffrey Bland
Amy Jennae Hall
Veera Konda
Linda Pacioretty
Anu Desai
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Metaproteomics Llc, Matthew L Tripp, John G Babish, Jeffrey Bland, Amy Jennae Hall, Veera Konda, Linda Pacioretty, Anu Desai filed Critical Metaproteomics Llc
Priority to EP06839296A priority Critical patent/EP1976552A4/en
Priority to AU2006321727A priority patent/AU2006321727A1/en
Priority to JP2008544582A priority patent/JP2009518439A/en
Priority to NZ568860A priority patent/NZ568860A/en
Priority to CA002632684A priority patent/CA2632684A1/en
Publication of WO2007067812A2 publication Critical patent/WO2007067812A2/en
Publication of WO2007067812A3 publication Critical patent/WO2007067812A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Abstract

Botanical compounds to modulate kinase activity are disclosed. The compounds and methods disclosed also inhibit expression of COX-2, inhibit synthesis of prostaglandins selectively in target cells, and inhibit inflammatory response selectively. The compositions contain at least one fraction isolated or derived from hops or Acacia.
PCT/US2006/047196 2005-12-09 2006-12-11 Protein kinase modulation by hops and acacia products WO2007067812A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
EP06839296A EP1976552A4 (en) 2005-12-09 2006-12-11 Protein kinase modulation by hops and acacia products
AU2006321727A AU2006321727A1 (en) 2005-12-09 2006-12-11 Protein kinase modulation by hops and Acacia products
JP2008544582A JP2009518439A (en) 2005-12-09 2006-12-11 Protein kinase regulation by hops and acacia products
NZ568860A NZ568860A (en) 2005-12-09 2006-12-11 Protein kinase modulation by hops and acacia products
CA002632684A CA2632684A1 (en) 2005-12-09 2006-12-11 Protein kinase modulation by hops and acacia products

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US74893105P 2005-12-09 2005-12-09
US60/748,931 2005-12-09

Publications (2)

Publication Number Publication Date
WO2007067812A2 WO2007067812A2 (en) 2007-06-14
WO2007067812A3 true WO2007067812A3 (en) 2008-02-28

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/047196 WO2007067812A2 (en) 2005-12-09 2006-12-11 Protein kinase modulation by hops and acacia products

Country Status (7)

Country Link
US (2) US20070154576A1 (en)
EP (1) EP1976552A4 (en)
JP (1) JP2009518439A (en)
AU (1) AU2006321727A1 (en)
CA (1) CA2632684A1 (en)
NZ (1) NZ568860A (en)
WO (1) WO2007067812A2 (en)

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CA2632684A1 (en) 2007-06-14
US20070154576A1 (en) 2007-07-05
WO2007067812A2 (en) 2007-06-14
NZ568860A (en) 2012-09-28
EP1976552A2 (en) 2008-10-08
JP2009518439A (en) 2009-05-07
AU2006321727A1 (en) 2007-06-14
US20080031986A1 (en) 2008-02-07

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