WO2004078163A3 - Pharmaceutical co-crystal compositions of drugs such as carbamazepine, celecoxib, olanzapine, itraconazole, topiramate, modafinil, 5-fluorouracil, hydrochlorothiazide, acetaminophen, aspirin, flurbiprofen, phenytoin and ibuprofen - Google Patents
Pharmaceutical co-crystal compositions of drugs such as carbamazepine, celecoxib, olanzapine, itraconazole, topiramate, modafinil, 5-fluorouracil, hydrochlorothiazide, acetaminophen, aspirin, flurbiprofen, phenytoin and ibuprofen Download PDFInfo
- Publication number
- WO2004078163A3 WO2004078163A3 PCT/US2004/006288 US2004006288W WO2004078163A3 WO 2004078163 A3 WO2004078163 A3 WO 2004078163A3 US 2004006288 W US2004006288 W US 2004006288W WO 2004078163 A3 WO2004078163 A3 WO 2004078163A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- ester
- api
- acid
- heterocyclic ring
- amine
- Prior art date
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
Abstract
Priority Applications (17)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/546,963 US20070059356A1 (en) | 2002-05-31 | 2004-02-26 | Pharmaceutical co-crystal compositions of drugs such as carbamazepine, celecoxib, olanzapine, itraconazole, topiramate, modafinil, 5-fluorouracil, hydrochlorothiazide, acetaminophen, aspirin, flurbiprofen, phenytoin and ibuprofen |
EP04715190A EP1631260A2 (en) | 2003-02-28 | 2004-02-26 | Pharmaceutical co-crystal compositions of drugs such as carbamazepine, celecoxib, olanzapine, itraconazole, topiramate, modafinil, 5-fluorouracil, hydrochlorothazide, acetaminophen, aspirin, flurbiprofen, phenytoin and ibuprofen |
CA002514733A CA2514733A1 (en) | 2003-02-28 | 2004-02-26 | Pharmaceutical co-crystal compositions of drugs such as carbamazepine, celecoxib, olanzapine, itraconazole, topiramate, modafinil, 5-fluorouracil, hydrochlorothiazide, acetaminophen, aspirin, flurbiprofen, phenytoin and ibuprofen |
JP2006508979A JP2007524596A (en) | 2003-02-28 | 2004-02-26 | Co-crystal pharmaceutical composition |
US10/551,014 US20060223794A1 (en) | 2002-02-15 | 2004-03-31 | Novel olanzapine forms and related methods of treatment |
PCT/US2004/009947 WO2004089313A2 (en) | 2003-04-01 | 2004-03-31 | Novel olanzapine forms and related methods of treatment |
US10/926,842 US7446107B2 (en) | 2002-02-15 | 2004-08-26 | Crystalline forms of conazoles and methods of making and using the same |
PCT/US2004/028456 WO2005092884A1 (en) | 2004-02-26 | 2004-09-01 | Novel crystalline forms of conazoles and methods of making and using the same |
EP04782868A EP1718640A4 (en) | 2004-02-26 | 2004-09-01 | Novel crystalline forms of conazoles and methods of making and using the same |
JP2007500742A JP2007525502A (en) | 2004-02-26 | 2004-09-01 | Novel crystalline forms of conazoles and methods for their production and use |
JP2006525508A JP4842819B2 (en) | 2003-09-04 | 2004-09-04 | Modafinil composition |
EP20040783308 EP1670753A4 (en) | 2003-09-04 | 2004-09-04 | Modafinil compositions |
IL173575A IL173575A0 (en) | 2003-09-04 | 2006-02-07 | Modafinil compositions |
NO20060669A NO20060669L (en) | 2003-09-11 | 2006-02-10 | Modafinilsammensetninger |
US12/234,420 US20090088443A1 (en) | 2002-02-15 | 2008-09-19 | Novel crystalline forms of conazoles and methods of making and using the same |
IL199140A IL199140A (en) | 2003-09-04 | 2009-06-03 | Modafinil compositions |
US12/792,415 US20100311701A1 (en) | 2002-02-15 | 2010-06-02 | Pharmaceutical Co-Crystal Compositions |
Applications Claiming Priority (26)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US45121303P | 2003-02-28 | 2003-02-28 | |
US60/451,213 | 2003-02-28 | ||
PCT/US2003/006662 WO2003074474A2 (en) | 2002-03-01 | 2003-03-03 | Multiple-component solid phases containing at least one active pharmaceutical ingredient |
USPCT/US03/06662 | 2003-03-03 | ||
US45602703P | 2003-03-18 | 2003-03-18 | |
US60/456,027 | 2003-03-18 | ||
US46396203P | 2003-04-18 | 2003-04-18 | |
US60/463,962 | 2003-04-18 | ||
US10/449,307 | 2003-05-30 | ||
US10/449,307 US7078526B2 (en) | 2002-05-31 | 2003-05-30 | CIS-itraconazole crystalline forms and related processes, pharmaceutical compositions and methods |
US10/601,092 | 2003-06-20 | ||
PCT/US2003/019574 WO2004000284A1 (en) | 2002-06-21 | 2003-06-20 | Pharmaceutical compositions with improved dissolution |
USPCT/US03/19574 | 2003-06-20 | ||
US10/601,092 US20050025791A1 (en) | 2002-06-21 | 2003-06-20 | Pharmaceutical compositions with improved dissolution |
US48706403P | 2003-07-11 | 2003-07-11 | |
US60/487,064 | 2003-07-11 | ||
USPCT/US03/27772 | 2003-09-04 | ||
PCT/US2003/027772 WO2004078161A1 (en) | 2003-02-28 | 2003-09-04 | Pharmaceutical co-crystal compositions of drugs such as carbamazeptine, celecoxib, olanzapine, itraconazole, topiramate, modafinil, 5-fluorouracil, hydrochlorothiazide, acetaminophen, aspirin, flurbiprofen, phenytoin and ibuprofen |
US10/660,202 US7927613B2 (en) | 2002-02-15 | 2003-09-11 | Pharmaceutical co-crystal compositions |
US10/660,202 | 2003-09-11 | ||
US50820803P | 2003-10-02 | 2003-10-02 | |
US60/508,208 | 2003-10-02 | ||
USPCT/US03/41273 | 2003-12-24 | ||
PCT/US2003/041273 WO2004061433A1 (en) | 2002-12-30 | 2003-12-24 | Pharmaceutical compositions with improved dissolution |
US54275204P | 2004-02-06 | 2004-02-06 | |
US60/542,752 | 2004-02-06 |
Related Parent Applications (6)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2003/006662 Continuation-In-Part WO2003074474A2 (en) | 2002-02-15 | 2003-03-03 | Multiple-component solid phases containing at least one active pharmaceutical ingredient |
US10/449,307 Continuation-In-Part US7078526B2 (en) | 2002-02-15 | 2003-05-30 | CIS-itraconazole crystalline forms and related processes, pharmaceutical compositions and methods |
US10/601,092 Continuation-In-Part US20050025791A1 (en) | 2002-02-15 | 2003-06-20 | Pharmaceutical compositions with improved dissolution |
US10/637,829 Continuation-In-Part US20040053853A1 (en) | 2002-02-15 | 2003-08-08 | Topiramate salts and compositions comprising and methods of making and using the same |
PCT/US2003/027772 Continuation-In-Part WO2004078161A1 (en) | 2002-02-15 | 2003-09-04 | Pharmaceutical co-crystal compositions of drugs such as carbamazeptine, celecoxib, olanzapine, itraconazole, topiramate, modafinil, 5-fluorouracil, hydrochlorothiazide, acetaminophen, aspirin, flurbiprofen, phenytoin and ibuprofen |
US10/660,202 Continuation-In-Part US7927613B2 (en) | 2002-02-15 | 2003-09-11 | Pharmaceutical co-crystal compositions |
Related Child Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US10/601,092 Continuation-In-Part US20050025791A1 (en) | 2002-02-15 | 2003-06-20 | Pharmaceutical compositions with improved dissolution |
US10/926,842 Continuation-In-Part US7446107B2 (en) | 2002-02-15 | 2004-08-26 | Crystalline forms of conazoles and methods of making and using the same |
US12/792,415 Continuation US20100311701A1 (en) | 2002-02-15 | 2010-06-02 | Pharmaceutical Co-Crystal Compositions |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2004078163A2 WO2004078163A2 (en) | 2004-09-16 |
WO2004078163A3 true WO2004078163A3 (en) | 2005-01-20 |
Family
ID=56290526
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2004/006288 WO2004078163A2 (en) | 2002-02-15 | 2004-02-26 | Pharmaceutical co-crystal compositions of drugs such as carbamazepine, celecoxib, olanzapine, itraconazole, topiramate, modafinil, 5-fluorouracil, hydrochlorothiazide, acetaminophen, aspirin, flurbiprofen, phenytoin and ibuprofen |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP1631260A2 (en) |
JP (1) | JP2007524596A (en) |
CA (1) | CA2514733A1 (en) |
WO (1) | WO2004078163A2 (en) |
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US8555875B2 (en) | 2008-12-23 | 2013-10-15 | Map Pharmaceuticals, Inc. | Inhalation devices and related methods for administration of sedative hypnotic compounds |
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Also Published As
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EP1631260A2 (en) | 2006-03-08 |
WO2004078163A2 (en) | 2004-09-16 |
JP2007524596A (en) | 2007-08-30 |
CA2514733A1 (en) | 2004-09-16 |
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