CN102646266A - Image processing method - Google Patents

Image processing method Download PDF

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Publication number
CN102646266A
CN102646266A CN2012100309514A CN201210030951A CN102646266A CN 102646266 A CN102646266 A CN 102646266A CN 2012100309514 A CN2012100309514 A CN 2012100309514A CN 201210030951 A CN201210030951 A CN 201210030951A CN 102646266 A CN102646266 A CN 102646266A
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China
Prior art keywords
blood vessel
image
threshold value
organ
choose
Prior art date
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Pending
Application number
CN2012100309514A
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Chinese (zh)
Inventor
梁萍
鲁通
类成龙
孙云娜
李寅岩
吴文波
薛劲
于晓玲
程志刚
韩治宇
刘方义
于杰
穆梦娟
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Chinese PLA General Hospital
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Chinese PLA General Hospital
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Priority to CN2012100309514A priority Critical patent/CN102646266A/en
Publication of CN102646266A publication Critical patent/CN102646266A/en
Pending legal-status Critical Current

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Abstract

The invention relates to an image processing method. Images are organ computed tomography (CT) images from which blood vessels can be seen. The method comprises the following steps that: the blood vessel dividing operation based on a threshold value comprises the steps of: (1) selecting seed points, (2) determining the threshold value, and (3) dividing the blood vessels; and the blood vessel rebuilding operation based on a model comprises the following steps of: (1) rebuilding blood vessels on the basis of the model, (2) extracting a center line, and (3) dividing organs and displaying the blood vessels.

Description

A kind of method of handling image
Technical field
The present invention relates to a kind of method of utilizing the image-guided device processes image of ablation.
Background technology
In recent years; Under image-guided through skin thermal ablation therapy method rely on that its Wicresoft, safety, complete tumor necrosis rate in oncotherapy is high, good effect and do not have the toxic and side effect of chemotherapy, radiotherapy; Little to normal tissue injury; And can activate the remarkable advantages such as antineoplastic immune of enhancing body, become the important component part of modern tumor therapeuticing method.
Under image-guided is that the puncture degree of accuracy is required much skill through the heating ablation of skin tumour.The enforcement of its treatment need be before art according to the imaging examination planning that undergos surgery, select suitable puncture approach, confirm that simultaneously needing to form what ablation area could cover whole tumour fully.The guiding that in art, then need rely on iconography is inner with the planning implantation tumour of ablation needle before according to art.Postoperative need be judged whether tumour ablation is complete, have or not the residual or edge recurrence of tumour.No matter the surgery planning before the art, the location of the puncture in the art still are the experience that the recruitment evaluation of postoperative all highly relies on the patient, receive the interference of various human factors, directly influence the curative effect of heating ablation.Thereby be necessary to adopt new technology and method to overcome the interference of various human factors, and solving in the planning of art prescience, the art and accurately locate, the difficult problem of postoperative effect assessment is based upon image-guided tumour heating ablation on more objective, the accurate basis.
Summary of the invention
On this basis, we have researched and developed the image-guided equipment of a kind of ablation.This equipment handles through 3-dimensional image and analytical technology is come directly perceived, clear, arbitrarily angled ground display space neighbouring relationship; And carry out the surgery planning before qualitative assessment carries out art through calculating; And combine the intervene operation navigational system to carry out the accurate location in the centesis, can also through judge tumour ablation whether fully, have or not the residual or edge recurrence of tumour to carry out effective surgery to assess.The various difficult problems that the proposition of this equipment has effectively solved before the art, in the art, postoperative runs into have been based upon image-guided tumour heating ablation on more objective, the accurate basis.
Utilize the image-guided equipment of above-mentioned ablation to carry out the method for handling image of the present invention, said image said method comprising the steps of for seeing the organ CT image of blood vessel:
1) the blood vessel segmentation operation steps based on threshold value is following:
(1) chooses seed points
(2) confirm threshold value
Promptly confirm the last lower threshold value of blood vessel, move to mouse in the blood vessel, confirm threshold range, the click preview is seen to check the mark and is cut effect, and the adjustment threshold value is up to obtaining comparatively ideal blood vessel segmentation data.
(3) blood vessel segmentation
Button is cut apart in click after having confirmed threshold value, waits for the blood vessel data of cutting apart completion.
2) the reconstructing blood vessel operation steps based on model is following:
(1) based on the reconstructing blood vessel of model
Blood vessel after completion is cut apart is more coarse; Can't accomplish follow-up various analyses, therefore need rebuild, at first choose the starting point (being generally a point) of blood vessel blood vessel; Choose the terminating point of blood vessel then according to your needed vessel branch, the branch that does not choose does not then rebuild.
(2) center line extracts
Be used for morphological analysis and reconstructing blood vessel.
(3) organ is cut apart and the blood vessel demonstration
Can with organ as requested organ be divided into multistage, show, and the corresponding blood vessel of each organ intersegmental part is also shown with various colors with various colors.
The invention solves in the planning of art prescience, the art and accurately locate, the difficult problem of postoperative effect assessment has overcome the interference of various human factors, has directly improved the curative effect of heating ablation, and image-guided tumour heating ablation is based upon on more objective, the accurate basis.
Description of drawings
Fig. 1 is a structural representation of the present invention;
Fig. 2 is the structural representation of processor of the present invention;
Fig. 3 is image cutting figure;
Fig. 4 is three-dimensional volume rendered;
Fig. 5 is radiographic measurement figure;
Fig. 6 is a registration figure;
Fig. 7 is Interactive Segmentation figure;
Fig. 8 is blood vessel segmentation figure;
Fig. 9 is cut apart figure for hepatic segments;
Figure 10 is a vessel graph in the liver;
Figure 11 is the tumor shape size and arrives each piping system bee-line figure;
Figure 12 is secure border figure;
Figure 13 is three-dimensional PDF report figure;
Figure 14 is the surgical navigational synoptic diagram;
Figure 15 is the color coding analysis chart of ablation areas;
Figure 16 is a tumour ablation surgical effect evaluation graph.
Embodiment
Below in conjunction with accompanying drawing and concrete embodiment the image-guided equipment of ablation of the present invention is further described, but can not be with this as restriction protection scope of the present invention.
Referring to Fig. 1,2, the image-guided equipment of ablation of the present invention comprises processor 1, display screen 2, keyboard 3 and mouse 4.Wherein, processor 1 is a core component of the present invention, and its inside comprises image collection device 5, image processor 6 and Image Management device 7, and image collection device 5 is used to gather image information, and the image information that collects is transferred to image processor 6; Image processor 6 will be gathered the image information that comes by image collection device 5 and process, handles, to obtain the image that the user needs; Image through processing, processing directly shows 2 by display screen, transfers to Image Management device 7 simultaneously and stores, and calls at any time in order to the user.Display screen 2, keyboard 3 and mouse 4 all are connected with processor 1, and display screen 2 is as the output device of processor 1, and show image is beneficial to the user and browses, judges, analyzes intuitively; Keyboard 3 and the input equipment of mouse 4 as processor can manipulation processor 1, make demand and the judgement of user according to oneself, and image is processed, handled.
Image processor 6 comprises image two-dimensional process device 8, image three-dimensional treating apparatus 9, image measuring device 10, Image registration device 11, image segmenting device 12.
Referring to Fig. 3, display screen 2 is made up of three two dimension view windows and a 3-D view window, and three two dimension view windows are respectively cross-section position window, sagittal plain window, crown position window.
Image two-dimensional process device 8 is made up of image base conditioning device and image Scissoring device two parts.Image base conditioning device comprises to the Filtering Processing of single width image and to the arithmetical operation of two width of cloth images to be handled.The image Scissoring device generally can be analyzed all image datas, reaches mode of operation more flexibly for obtaining better contrast, and the user can carry out trimming operation and select the subregion data to carry out the image processing operation.
The image three-dimensional treating apparatus reaches " video production " two parts by " volume drawing " and forms.Each point in the middle of the volume data can distribute the emission and the absorption parameter of a light.Like this, through the propagation of portion in vivo of simulation light, just can realize the demonstration of volume data under the condition of any visual angle.The image processing result can preserve video or view screenshotss get off through making video record.
Image measuring device can make user and bidimensional image or contain storehouse and individual image dough sheet of the three-dimensional of graphics plane data type carries out interactive operation.It can measuring distance, angle, path and some geometric figures.After carrying out measuring operation, can the identical or different measurement pattern with the selected correction of image be preserved, in order in the future used.When on image, having drawn a plurality of figure, current application graphic presentation is red, and all the other Graphics Applications then are shown as white, and the displayed value on the image is the rreturn value of current application figure.All measurement pattern all can each self-generating the node of an image tree in data management system, show.The single measurement pattern that no longer needs or image can be deleted in data management system one by one or as one group of whole deletion.
The Image registration device reaches " non-rigid body registration " three parts by " some registration ", " rigid body registration " and forms.The medical image registration is meant one group of medical image behind spatial alternation, makes it and another group keep corresponding point on the motionless medical image to reach consistent on the space.Keep motionless being called with reference to image, conversion is called unsteady image.The result of registration is applied to the image that floats.
The image segmenting device can be that anatomical structure and pathologic structure establishment are cut apart on the medical image of human body.Comprise Interactive Segmentation and blood vessel segmentation two parts.Below be example with the liver, the principle of work of image segmenting device is described.
Blood vessel segmentation comprises based on the blood vessel segmentation of threshold value with based on two steps of reconstructing blood vessel of model.
The image basic demand is that blood vessel was strengthened the CT data; Bed thickness≤2mm; And blood vessel CT voxel mean value is greater than 30 gray-scale values of peripheral organs, can see that basically blood vessel just can be used for cutting apart (nuclear-magnetism is also passable, does not advise adopting the nuclear-magnetism image but operating personnel are had relatively high expectations).
Operation steps is following:
(1) chooses seed points
(2) confirm threshold value
Promptly confirm the last lower threshold value of blood vessel, move to mouse in the blood vessel, confirm threshold range, the click preview is seen to check the mark and is cut effect, and the adjustment threshold value is up to obtaining comparatively ideal blood vessel segmentation data.
(3) blood vessel segmentation
Button is cut apart in click after having confirmed threshold value, waits for the blood vessel data of cutting apart completion.
(4) based on the reconstructing blood vessel of model
Blood vessel after completion is cut apart is more coarse, can't accomplish follow-up various analyses, therefore need rebuild blood vessel; At first choose the starting point (being generally a point) of blood vessel at three dimensional window; Choose the terminating point of blood vessel then according to your needed vessel branch, the branch that does not choose does not then rebuild, and chooses seed points and clicks the reconstruction button afterwards; This step is consuming time longer, waits the blood vessel result after completion to be calculated just can be seen reconstruction.
(5) center line extracts
Be used for morphological analysis and reconstructing blood vessel.
(6) hepatic segments is cut apart
Can liver be divided into eight sections show with liver according to medical requirement, and the inner corresponding blood vessel of each hepatic segments is also shown with various colors with various colors.

Claims (1)

1. method of handling image, said image said method comprising the steps of for seeing the organ CT image of blood vessel:
1) the blood vessel segmentation operation steps based on threshold value is following:
(1) chooses seed points
(2) confirm threshold value
Promptly confirm the last lower threshold value of blood vessel, move to mouse in the blood vessel, confirm threshold range, the click preview is seen to check the mark and is cut effect, and the adjustment threshold value is up to obtaining comparatively ideal blood vessel segmentation data.
(3) blood vessel segmentation
Button is cut apart in click after having confirmed threshold value, waits for the blood vessel data of cutting apart completion.
2) the reconstructing blood vessel operation steps based on model is following:
(1) based on the reconstructing blood vessel of model
Blood vessel after completion is cut apart is more coarse; Can't accomplish follow-up various analyses, therefore need rebuild, at first choose the starting point (being generally a point) of blood vessel blood vessel; Choose the terminating point of blood vessel then according to your needed vessel branch, the branch that does not choose does not then rebuild.
(2) center line extracts
Be used for morphological analysis and reconstructing blood vessel.
(3) organ is cut apart and the blood vessel demonstration
Can with organ as requested organ be divided into multistage, show, and the corresponding blood vessel of each organ intersegmental part is also shown with various colors with various colors.
CN2012100309514A 2012-02-10 2012-02-10 Image processing method Pending CN102646266A (en)

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Application Number Priority Date Filing Date Title
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CN102646266A true CN102646266A (en) 2012-08-22

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103970988B (en) * 2014-04-14 2017-05-24 中国人民解放军总医院 Ablation needle insertion path planning method and system
CN109448004A (en) * 2018-10-26 2019-03-08 强联智创(北京)科技有限公司 A kind of intercept method and system of the intracranial vessel image based on center line
CN109934913A (en) * 2019-03-19 2019-06-25 肖仁德 The virtual intervention support method for implantation of intracranial aneurysm, device, computer equipment
CN109961850A (en) * 2019-03-19 2019-07-02 肖仁德 A kind of method, apparatus, computer equipment for assessing rupture of intracranial aneurysm risk

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005055141A1 (en) * 2003-11-26 2005-06-16 Vital Images, Inc. Segmenting and displaying tubular vessels in volumetric imaging data
CN101393644A (en) * 2008-08-15 2009-03-25 华中科技大学 Hepatic portal vein tree modeling method and system thereof
CN101601585A (en) * 2009-07-02 2009-12-16 厦门强本科技有限公司 Liver subsection volume measuring method based on CT enhanced ct scans technology

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005055141A1 (en) * 2003-11-26 2005-06-16 Vital Images, Inc. Segmenting and displaying tubular vessels in volumetric imaging data
CN101393644A (en) * 2008-08-15 2009-03-25 华中科技大学 Hepatic portal vein tree modeling method and system thereof
CN101601585A (en) * 2009-07-02 2009-12-16 厦门强本科技有限公司 Liver subsection volume measuring method based on CT enhanced ct scans technology

Non-Patent Citations (1)

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Title
伍亚军等: "基于MRI的动物肝脏脉管分割与三维重建", 《中国医学影像技术》, vol. 21, no. 8, 31 August 2005 (2005-08-31), pages 1275 - 1277 *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103970988B (en) * 2014-04-14 2017-05-24 中国人民解放军总医院 Ablation needle insertion path planning method and system
CN109448004A (en) * 2018-10-26 2019-03-08 强联智创(北京)科技有限公司 A kind of intercept method and system of the intracranial vessel image based on center line
CN109934913A (en) * 2019-03-19 2019-06-25 肖仁德 The virtual intervention support method for implantation of intracranial aneurysm, device, computer equipment
CN109961850A (en) * 2019-03-19 2019-07-02 肖仁德 A kind of method, apparatus, computer equipment for assessing rupture of intracranial aneurysm risk

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Application publication date: 20120822