CA2383539A1 - Methods for producing laminated elastin, elastin-based materials and tropoelastin products for repairing and/or replacing tissue - Google Patents
Methods for producing laminated elastin, elastin-based materials and tropoelastin products for repairing and/or replacing tissue Download PDFInfo
- Publication number
- CA2383539A1 CA2383539A1 CA002383539A CA2383539A CA2383539A1 CA 2383539 A1 CA2383539 A1 CA 2383539A1 CA 002383539 A CA002383539 A CA 002383539A CA 2383539 A CA2383539 A CA 2383539A CA 2383539 A1 CA2383539 A1 CA 2383539A1
- Authority
- CA
- Canada
- Prior art keywords
- elastin
- laminated
- unlaminated
- based materials
- materials
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108010014258 Elastin Proteins 0.000 title abstract 15
- 239000000463 material Substances 0.000 title abstract 12
- 102000016942 Elastin Human genes 0.000 title abstract 10
- 229920002549 elastin Polymers 0.000 title abstract 10
- 102100033167 Elastin Human genes 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 2
- 239000000853 adhesive Substances 0.000 abstract 2
- 230000001070 adhesive effect Effects 0.000 abstract 2
- 229920001651 Cyanoacrylate Polymers 0.000 abstract 1
- -1 alkoxy alkyl cyanoacrylate Chemical compound 0.000 abstract 1
- 230000004927 fusion Effects 0.000 abstract 1
- 239000003292 glue Substances 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 239000011185 multilayer composite material Substances 0.000 abstract 1
- 239000000758 substrate Substances 0.000 abstract 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B9/00—Layered products comprising a layer of a particular substance not covered by groups B32B11/00 - B32B29/00
- B32B9/02—Layered products comprising a layer of a particular substance not covered by groups B32B11/00 - B32B29/00 comprising animal or vegetable substances, e.g. cork, bamboo, starch
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
- A61L24/06—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B2307/00—Properties of the layers or laminate
- B32B2307/50—Properties of the layers or laminate having particular mechanical properties
- B32B2307/582—Tearability
- B32B2307/5825—Tear resistant
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B2307/00—Properties of the layers or laminate
- B32B2307/70—Other properties
- B32B2307/726—Permeability to liquids, absorption
- B32B2307/7265—Non-permeable
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B2535/00—Medical equipment, e.g. bandage, prostheses, catheter
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B2556/00—Patches, e.g. medical patches, repair patches
Abstract
The invention is directed to a method including the steps of providing at least one layer of unlaminated elastin or un-laminated elastin-based materials or unlaminated tropoelastin materials.
Then, the unlaminated elastin or unlaminated elastin-based materials or unlaminated tropoelastin materials is subjected to heating and pressing steps. The pressing step of the present invention is preferably conducted in the presence of steam. The laminated elastin or laminated elastin-based materials or laminated tropoe-lastin materials preferably comprises a multi-layer composite material.
Typically, the step of adhering with an adhesive material the laminated elastin or laminated elastin-based materials or laminated tropoelastin materials is employed in order to achieve a water-tight engagement with the tissue substrate. A biogradable cyanocrylate glue is generally used in order to achieve quick and easy way to secure the patch in place and provide watertight fusion instantly.
Preferably, the adhesive material comprises an alkoxy alkyl cyanoacrylate material.
Then, the unlaminated elastin or unlaminated elastin-based materials or unlaminated tropoelastin materials is subjected to heating and pressing steps. The pressing step of the present invention is preferably conducted in the presence of steam. The laminated elastin or laminated elastin-based materials or laminated tropoe-lastin materials preferably comprises a multi-layer composite material.
Typically, the step of adhering with an adhesive material the laminated elastin or laminated elastin-based materials or laminated tropoelastin materials is employed in order to achieve a water-tight engagement with the tissue substrate. A biogradable cyanocrylate glue is generally used in order to achieve quick and easy way to secure the patch in place and provide watertight fusion instantly.
Preferably, the adhesive material comprises an alkoxy alkyl cyanoacrylate material.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13657399P | 1999-05-28 | 1999-05-28 | |
US60/136,573 | 1999-05-28 | ||
PCT/US2000/014621 WO2000073399A1 (en) | 1999-05-28 | 2000-05-25 | Methods for producing laminated elastin, elastin-based materials and tropoelastin products for repairing and/or replacing tissue |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2383539A1 true CA2383539A1 (en) | 2000-12-07 |
CA2383539C CA2383539C (en) | 2007-12-04 |
Family
ID=22473421
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002383539A Expired - Fee Related CA2383539C (en) | 1999-05-28 | 2000-05-25 | Methods for producing laminated elastin, elastin-based materials and tropoelastin products for repairing and/or replacing tissue |
Country Status (5)
Country | Link |
---|---|
US (1) | US6667051B1 (en) |
EP (1) | EP1196510A4 (en) |
AU (1) | AU765879B2 (en) |
CA (1) | CA2383539C (en) |
WO (1) | WO2000073399A1 (en) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001010314A2 (en) * | 1999-08-05 | 2001-02-15 | Broncus Technologies, Inc. | Methods and devices for creating collateral channels in the lungs |
US7422584B2 (en) * | 2002-07-05 | 2008-09-09 | Broncus Technologies, Inc. | Extrapleural airway device and method |
US6808707B2 (en) * | 2000-02-04 | 2004-10-26 | Matrix Design | Wound healing compositions and methods using tropoelastin and lysyl oxidase |
US9522217B2 (en) | 2000-03-15 | 2016-12-20 | Orbusneich Medical, Inc. | Medical device with coating for capturing genetically-altered cells and methods for using same |
US8088060B2 (en) | 2000-03-15 | 2012-01-03 | Orbusneich Medical, Inc. | Progenitor endothelial cell capturing with a drug eluting implantable medical device |
WO2004038004A2 (en) * | 2002-10-23 | 2004-05-06 | The Research Foundation Of State University Of Newyork | Fibrin-based tissue-engineered vasculature |
US8308682B2 (en) | 2003-07-18 | 2012-11-13 | Broncus Medical Inc. | Devices for maintaining patency of surgically created channels in tissue |
US20050182443A1 (en) | 2004-02-18 | 2005-08-18 | Closure Medical Corporation | Adhesive-containing wound closure device and method |
US20060009099A1 (en) | 2004-07-12 | 2006-01-12 | Closure Medical Corporation | Adhesive-containing wound closure device and method |
US8409167B2 (en) | 2004-07-19 | 2013-04-02 | Broncus Medical Inc | Devices for delivering substances through an extra-anatomic opening created in an airway |
WO2006019063A1 (en) * | 2004-08-16 | 2006-02-23 | Showa Denko K.K. | Magnetic recording medium and magnetic recording and reproducing device |
US20060257447A1 (en) * | 2005-03-09 | 2006-11-16 | Providence Health System | Composite graft |
US20090169593A1 (en) * | 2005-10-19 | 2009-07-02 | Biomedical Research Services, Inc. | Method of using and producing tropoelastin and tropoelastin biomaterials |
US20070225795A1 (en) * | 2006-03-24 | 2007-09-27 | Juan Granada | Composite vascular prosthesis |
CA2669114C (en) | 2006-11-13 | 2014-12-16 | The University Of Sydney | Use of tropoelastin for repair or restoration of tissue |
HUE047235T2 (en) | 2009-03-10 | 2020-04-28 | Allergan Pharmaceuticals Int Ltd | Injectable biomaterials |
US9486229B2 (en) | 2011-05-13 | 2016-11-08 | Broncus Medical Inc. | Methods and devices for excision of tissue |
US8709034B2 (en) | 2011-05-13 | 2014-04-29 | Broncus Medical Inc. | Methods and devices for diagnosing, monitoring, or treating medical conditions through an opening through an airway wall |
WO2013078235A1 (en) | 2011-11-23 | 2013-05-30 | Broncus Medical Inc | Methods and devices for diagnosing, monitoring, or treating medical conditions through an opening through an airway wall |
US9688741B2 (en) | 2012-10-23 | 2017-06-27 | Elastagen Pty Ltd | Elastic hydrogel |
ES2860023T3 (en) | 2012-12-10 | 2021-10-04 | Allergan Pharmaceuticals Int Ltd | Fabrication of scalable three-dimensional elastic constructs |
CN110464837A (en) * | 2013-08-13 | 2019-11-19 | 爱力根制药国际有限公司 | The regeneration of damaged tissues |
USD824525S1 (en) | 2014-09-25 | 2018-07-31 | Ethicon Llc | Release paper for wound treament devices |
US10792024B2 (en) | 2016-09-28 | 2020-10-06 | Ethicon, Inc. | Scaffolds with channels for joining layers of tissue at discrete points |
USD848624S1 (en) | 2016-09-29 | 2019-05-14 | Ethicon, Inc. | Release paper for wound treatment devices |
US10470934B2 (en) | 2016-09-29 | 2019-11-12 | Ethicon, Inc. | Methods and devices for skin closure |
US10687986B2 (en) | 2016-09-29 | 2020-06-23 | Ethicon, Inc. | Methods and devices for skin closure |
US10470935B2 (en) | 2017-03-23 | 2019-11-12 | Ethicon, Inc. | Skin closure systems and devices of improved flexibility and stretchability for bendable joints |
US11504446B2 (en) | 2017-04-25 | 2022-11-22 | Ethicon, Inc. | Skin closure devices with self-forming exudate drainage channels |
US10993708B2 (en) | 2018-07-31 | 2021-05-04 | Ethicon, Inc. | Skin closure devices with interrupted closure |
WO2023194333A1 (en) | 2022-04-04 | 2023-10-12 | Swiftpharma Bv | Recombinant spider silk-reinforced collagen proteins produced in plants and the use thereof |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3559652A (en) * | 1968-08-05 | 1971-02-02 | Minnesota Mining & Mfg | Method of adhesively repairing body tissue with alkoxyalkyl 2-cyanoacrylate |
US4187852A (en) | 1976-07-09 | 1980-02-12 | The University Of Alabama | Synthetic elastomeric insoluble cross-linked polypentapeptide |
US4132746A (en) | 1976-07-09 | 1979-01-02 | University Of Alabama, Birmingham Medical & Education Foundation | Synthetic elastomeric insoluble cross-linked polypentapeptide |
US4500700A (en) | 1981-10-02 | 1985-02-19 | The Board Of Trustees Of The University Of Alabama For The University Of Alabama In Birmingham | Elastomeric composite material comprising a polypentapeptide having an amino acid of opposite chirality in position three |
US4589882A (en) | 1983-09-19 | 1986-05-20 | Urry Dan W | Enzymatically crosslinked bioelastomers |
US5223420A (en) * | 1985-03-01 | 1993-06-29 | Institut National De La Sante Et De La Recherche Medicale | Elastin-based product, a procedure for its preparation and its biological applications; in particular as biomaterials and artificial supports |
US5064430A (en) | 1985-10-31 | 1991-11-12 | Uab Research Foundation | Polynonapeptide bioelastomers having an increased elastic modulus |
US4693718A (en) | 1985-10-31 | 1987-09-15 | University Of Alabama In Birmingham | Stimulation of chemotaxis by chemotactic peptides |
US4783523A (en) | 1986-08-27 | 1988-11-08 | Urry Dan W | Temperature correlated force and structure development of elastin polytetrapeptides and polypentapeptides |
US4870055A (en) | 1986-04-17 | 1989-09-26 | University Of Alabama At Birmingham | Segmented polypeptide bioelastomers to modulate elastic modulus |
US5336256A (en) | 1986-04-17 | 1994-08-09 | Uab Research Foundation | Elastomeric polypeptides as vascular prosthetic materials |
BG45286A1 (en) * | 1987-09-29 | 1989-05-15 | Nadka V Avramova | |
US5124155A (en) * | 1988-06-21 | 1992-06-23 | Chiron Ophthalmics, Inc. | Fibronectin wound-healing dressings |
FR2649982B1 (en) * | 1989-07-20 | 1991-09-27 | Inst Nat Sante Rech Med | ARTIFICIAL BIOLOGICAL MEMBRANE |
US6087552A (en) | 1994-11-15 | 2000-07-11 | Sisters Of Providence Of Oregon | Method of producing fused biomaterials and tissue |
US5989244A (en) * | 1994-11-15 | 1999-11-23 | Gregory; Kenton W. | Method of use of a sheet of elastin or elastin-based material |
US6372228B1 (en) * | 1994-11-15 | 2002-04-16 | Kenton W. Gregory | Method of producing elastin, elastin-based biomaterials and tropoelastin materials |
US6110212A (en) | 1994-11-15 | 2000-08-29 | Kenton W. Gregory | Elastin and elastin-based materials |
EP1011519A4 (en) * | 1997-02-07 | 2006-09-27 | Providence Health Sys Oregon | Method for using tropoelastin and for producing tropoelastin biomaterials |
JPH10264344A (en) * | 1997-03-28 | 1998-10-06 | Fuji Electric Co Ltd | Method and device for lamination |
-
2000
- 2000-05-25 CA CA002383539A patent/CA2383539C/en not_active Expired - Fee Related
- 2000-05-25 AU AU52974/00A patent/AU765879B2/en not_active Ceased
- 2000-05-25 US US09/979,868 patent/US6667051B1/en not_active Expired - Fee Related
- 2000-05-25 EP EP00937853A patent/EP1196510A4/en not_active Withdrawn
- 2000-05-25 WO PCT/US2000/014621 patent/WO2000073399A1/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
WO2000073399A1 (en) | 2000-12-07 |
AU5297400A (en) | 2000-12-18 |
CA2383539C (en) | 2007-12-04 |
AU765879B2 (en) | 2003-10-02 |
EP1196510A1 (en) | 2002-04-17 |
US6667051B1 (en) | 2003-12-23 |
EP1196510A4 (en) | 2007-01-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed |